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Abstract

Prognostic Factors and Survival of the Differentiated Thyroid Cancer: A Retrospective Study

Introduction: The thyroid cancer incidence is increased in recent years. Thyroid cancer approximately represents 1% of all cancer diagnosed patients yearly. Prediction of the thyroid malignancies was extend from most extremely visible differentiated carcinoma; papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC), to the minimal public aggressive, however extreme aggressively growing was an anaplastic type.

Aim of current work: The aim of our investigation is to determine the prognostic factors, which are effecting the long-term survival in patients with differentiated thyroid carcinoma (DTC).

Patients and methods: The retrospective investigation was done at the surgical department, Zagazig University. Two hundred and fifty patients were influenced for DTC from 2010 to 2018. All estimated patients were categorized into 167 for PTC and 93 for FTC. Data of 250 patients have been clarified during our retrospective study. Survival data and risk factors have been concluded from follow-up documents, and from the patients reviewing.

Results and Discussion: Follow-up 167 patients and their survival data underwent surgery for papillary carcinoma and follow 93 for follicular carcinoma, at the surgical department, Zagazig University. The 10 years survival was 87.9% and 84.0%, respectively. Follow up time is around ten years for 2 groups. Patients of papillary carcinoma (average age: 42.7 ± 16.0 years, male: 47, female 120: (male: female ratio 1: 2.5), however in patients were operated on for follicular carcinoma (average age: 48.5 ± 14.9 years, male: 29, female: 64, male: female ratio 1: 2.2). Our findings clarified a persistent elevation in the number of patients, together with elevated papillary carcinomas proportion, and through this period of study their elevation of early average which correlated completely with our statistics.

Conclusion: The outcome of PTC and FTC are comparatively well with decrease tumor-related mortality, and the survival average are get better through the past ten years because the consequence of broad prevalence recent diagnostic and curative protocols. After determining the predicted factors of survival gives us to make the suitable decision for every individualized surgical plan and the extent of the surgical intervention plane, whose needing for follow-up handling, the number or frequent follow-up care visits or outpatients clinics.


Author(s):

Hassan A Saad, Tamer Mohamed El-Shahidy* and Mohamed Abdallah Zaitoun



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